Prilosec is a Proton pump inhibitor (PPI) with the chemical name Omeprazole. PPIs are those medicines that inhibit the condition of acid reflux,

Acid reflux, generally known as heartburn occurs when the stomach acid enters the esophagus. It leaves a burning sensation in the tracheal canal. Prilosec comes in two different forms. The one is prescription Prilosec that cures severe conditions like ulcers. The Prilosec OTC only cures heartburn and can be found over the counter.


Prilosec OTC reduces the problem of ulcers and heartburn. It is used to treat esophageal discomfort caused by acid reflux. It lowers down the amount of stomach acid by restricting the production of the stomach wall enzyme that produces stomach acid.

This drug is not only effective against heartburn that occurs more twice a week but can also work as a preventive against ulcers.

Even if it is an over the counter medicine, it should be selected with care by going through the instruction leaflet with the medicine.

Take care of reading the ingredients to avoid any possible allergy.

The OTC variant doesn’t work very quickly, so there’s a chance that you don’t get immediately comforted after taking the medicine.


The medicine comes in the form of tablets, capsules, suspension and packet.

The dosages differ with the age and the condition for which the medicine is prescribed.

Adult dosage for ulcers is 20 mg once a day an hour before a meal.

The dosage for esophagitis is the same as for ulcers.

Erosive esophagitis that occurs due to GERD needs the same 20 mg per day.

Your doctor should determine this medicine’s dosage for your children.

The correct way to take the medicine is an hour before the meal time.

If you’re using a packet, dissolve it in two tablespoons of water and take it.

Do not use any other type of liquid such as a fruit juice or milk.

Side Effects:

The common side effects of Prilosec OTC include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Stomach ache
  • Headache

Other than these side effects, allergic reactions to this medicine can also occur, such as swelling of the face, arms, legs, lips or tongue.

Seizures or backache may develop.

Muscle spasms and dizziness may also occur.

In case of any of the uncommon side effects, immediately call your doctor for further investigation.

The continuous usage of this medicine for three years can leave you with a deficiency of vitamin B12.

Another side effect that can be caused by long term usage of Prilosec OTC is the development of fundic gland polyps which are small, smooth bumps in the upper portion of the stomach.


Prilosec OTC can cause severe allergic reactions if taken with specific antibiotics.

Never go for Prilosec OTC to cure any stomach discomfort while you are on an antibiotic.

If you see an unusual weight gain or swelling of any part of the body such as tongue, face, legs or wrist after taking this medicine, immediately inform your doctor.

It can occur due to a reaction of the medicine with the kidneys.

Please avoid using the medicine for longer periods because it can lead to vitamin B12 deficiency and growth inside the stomach known as fundic gland polyps.